#  Pardis Sabeti 

Professor of Organismic and Evolutionary Biology and of Immunology and Infectious Diseases

 

 

 



   ![Sabeti](/sites/g/files/omnuum12386/files/styles/hwp_4_5__320x400/public/2026-08/SabetParids.jpg?itok=KiDcNh2O) 

 



 





 

**Email**: [pardis@broadinstitute.org](mailto:pardis@broad.mit.edu)

#### **Website:**

[sabetilab.org](https://www.sabetilab.org/)   
**Lab Size**: 30

#### **Summary**

The Sabeti's lab aims to study the effect of natural selection on the human genome and on the genomes of other organisms and uncover the traits that have emerged to shape these species.

The goals of The Sabeti Lab are to use computational methods and genomics to understand mechanisms of evolutionary adaptation in humans and pathogens. We are pursuing these goals through 3 research foci:

(1) Developing analytical methods to detect and investigate evolution in the genomes of humans and other species  
(2) Examining host and viral genetic factors driving disease susceptibility to the devastating and deadly disease widespread in West Africa, Lassa hemorrhagic fever virus.   
(3) Investigating the genomes of microbes, including Lassa virus, Ebola virus, Plasmodium falciparum malaria, Vibrio cholerae, and Mycobacterioum tuberculosis to help in the development of intervention strategies.



 

 

 





 

 

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