Vlad Denic
Professor of Molecular and Cellular Biology
Harvard University
NorthWest Building, Room 445.30
52 Oxford Street
Boston, MA 02115
Tel: 617-496-6381
Email: vdenic@mcb.harvard.edu
Website:
http://www.deniclab.com/
Lab Size: Between 5 and 10
Summary
The Denic lab takes advantage of novel methodologies for studying large-scale genetic interactions in budding yeast as well as mass spectrometry-based characterization of natively-isolated protein complexes in order to identify the essential components required for several membrane-associated cellular processes. We then carry out targeted and systematic biochemical reconstitution strategies using the identified components in order to go from parts lists to functional and mechanistic insights.