William Shih
Professor of Biological Chemistry and Molecular Pharmacology
Email: william_shih@dfci.harvard.edu
Website:
shih.hms.harvard.edu
Lab Size: Between 10 and 15
Summary
We explore design principles for self-assembling molecular machines, primarily using structural DNA nanotechnology to build our model systems. We seek to apply our knowledge towards construction of artificial systems that help solve problems of biological and medical interest. Currently we focus on single-macromolecule identification and structure determination and on vaccine nanocarriers. For many applications, our present capabilities are too primitive. Thus we also investigate enabling technologies for increasing the complexity of programmable self-assembled systems.